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Bioavailability and delivery challenges One significant challenge with peptides is getting them to where they need to go

They can increase the risk of allergic reactions, infertility, and asthma

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ARA-290 (Cibinetide) holds FDA Orphan Drug Designation for sarcoidosis-associated neuropathic pain but has not received marketing authorisation or clinical approval from the MHRA, FDA, EMA, or any regulatory authority for routine therapeutic use